What is the active ingredient in Sudafed?
Sudafed Sinus and Nasal Decongestant contains the active ingredient Pseudoephedrine hydrochloride. Pseudoephedrine hydrochloride belongs to a group of medicines called sympathomimetic decongestants.
Pseudoephedrine is a drug that has been most commonly used as an ingredient in the previously over-the-counter medication, Sudafed, which is used as a nasal decongestant. Pseudoephedrine is present in some medications without a prescription, and it is available in drugstores behind the pharmacy counter.
Pseudoephedrine works by reducing the swelling of blood vessels in your nose. This helps mucus and air flow more freely in the cavities in your nose (sinuses), helping you to breathe more easily.
- ever had an allergic reaction to pseudoephedrine or any other medicine.
- high blood pressure (hypertension)
- heart disease.
- taken medicines for depression known as monoamine oxidase inhibitors (MAOIs) in the last 2 weeks.
- diabetes.
- an overactive thyroid gland (hyperthyroidism)
- Afrin, Dristan, Vicks Sinex (oxymetazoline)
- Sudafed PE, Suphedrin PE (phenylephrine)
- Silfedrine, Sudafed, Suphedrin (pseudoephedrine)
- Feeling or being sick. Try taking pseudoephedrine with or after a meal or snack. ...
- Headaches. Make sure you rest and drink plenty of fluids. ...
- A dry mouth. Chew sugar-free gum or suck sugar-free sweets.
- Feeling restless, nervous or shaky. ...
- Difficulty sleeping.
Is Sudafed or Mucinex better? Each medication is used for a different purpose. If you are experiencing nasal congestion, and you do not have any of the health conditions listed in the warnings above, you may want to take Sudafed. And if you are coughing up a lot of phlegm, you may want to take Mucinex.
It has an effect similar to ephedrine, but slightly weaker, and has a lower ability to induce tachycardia and increase systolic blood pressure. Its central effect is weaker than that of amphetamine, and its peripheral effect is similar to that of epinephrine [9].
Adults and children 12 years and over:
take 2 caplets every 4 hours. do not take more than 10 caplets in 24 hours.
This medicine works by shrinking swollen tissues and allowing mucus to drain.
Why do I feel worse after taking Sudafed?
Taking oral decongestants can raise your blood pressure and heart rate. Sometimes, even a couple doses can have these effects. Over time, high blood pressure can raise your risk for more serious problems, such as heart attacks.
Try rubbing diluted eucalyptus oil on the chest as a decongestant, or inhale eucalyptus or peppermint oil to clear stuffiness. Adding lavender, cedar, or lemon to steam may also soothe nasal passages. Inhaling menthol not only provides relief from nasal congestion, but might help inhibit infection as well.

A stuffy nose keeps sleep at bay, but so does pseudoephedrine, the main ingredient in many OTC decongestants (it's been known to cause insomnia).
Do oral decongestants cause rebound congestion, too? As for the varieties of oxymetazoline or phenylephrin that are taken orally, such as Sudafed, Dr. Ahmed says there's little risk of rebound congestion.
If possible, try to avoid taking medications like Sudafed before bed. They can make it harder to fall asleep. By taking them earlier in the day — or at least a few hours before bed — they're less likely to cause insomnia.
Mucinex D (Guaifenesin / Pseudoephedrine) is good if you have a stuffy nose and a cough with mucus, but it could keep you up at night. Clears your sinuses. Sudafed (Pseudoephedrine) relieves stuffy nose, but it could keep you up at night. Don't forget your photo ID or you won't be able to buy it in the drugstore.
The decongestant (Pseudoephedrine) in Zyrtec D (Cetirizine / Pseudoephedrine) is stronger than other decongestants.
Maximum-strength non-drowsy SUDAFED® provides lasting relief from congestion & pressure. Each tablet contains 240 mg of pseudoephedrine HCl, a nasal decongestant, and relieves symptoms for up to 24 hours. Adults and children 12 years and over: swallow one whole tablet with water every 24 hours.
Pseudoephedrine and derivatives have weak agonist alpha- and beta-adrenergic receptor activity but their main effects are caused by the release of endogenous noradrenaline from storage (2); thus, these chemicals act as sympathomimetic agents, leading to increases in heart rate, blood pressure and cardiac output.
Relieve your symptoms with SUDAFED. Our SUDAFED® Mucus Relief Triple Action Cold and Flu tablets help alleviate the symptoms of cold and flu by loosening chest mucus, easing nasal passage swelling to reduce that congested feeling as well as relieving pain.
What Sudafed is best for sinus drainage?
Sudafed is generally more effective at relieving nasal and sinus congestion than Sudafed PE, but it has more risks. Sudafed has some purchase restrictions, so it's only available behind the pharmacy counter. But Sudafed PE is readily available over the counter on pharmacy and grocery store shelves.
Decongestants. These medicines help reduce the swelling in your nasal passages and ease the stuffiness and sinus pressure. They come as nasal sprays, like naphazoline (Privine), oxymetazoline (Afrin, Dristan, Nostrilla, Vicks Sinus Nasal Spray), or phenylephrine (Neo-Synephrine, Rhinall, Sinex).
Its chemical structure is similar to that of amphetamine. However, the effects of Sudafed are slightly weaker than those of amphetamine. Additionally, pseudoephedrine can be used to make methamphetamine, a highly addictive stimulant.
Two commonly-used decongestants are pseudoephedrine (Sudafed) and phenylephrine (Sudafed PE). These medications work great to clear nasal passages and help us breathe better. But to our bodies, they look very similar to the stimulants discussed earlier and can have the same side effects, including anxiety.
The decongestant effect of pseudoephedrine is noticeable within 30 minutes of oral administration and reaches a peak within one to two hours. One immediate-release tablet of pseudoephedrine lasts anywhere from three to eight hours.
OTC medications that may help include: Decongestants. These work by narrowing blood vessels to help reduce inflammation and swelling that cause sinus congestion. Such OTC medications (Sudafed, others) are available in liquids, tablets and nasal sprays.
If your doctor has prescribed this medication, take it as directed. Take this medication by mouth with or without food, usually every 4 to 6 hours, as directed by the product package or by your doctor. Do not take more than 4 doses in a day. Dosage is based on your age, medical condition, and response to treatment.
Sudafed 12 Hour (pseudoephedrine ) is a decongestant medication. Decongestant drugs cause the mucous membranes in nasal passages to contract, which decreases swelling and secretion of mucus.
This happens when blood vessels in the cavities in your nose (sinuses) become swollen. Pseudoephedrine works by reducing this swelling and that helps mucus and air flow more freely.
Congestion tends to be worse at night because it is harder for the nose and sinuses to drain. This means that mucus pools in the head, making it harder to breathe and potentially causing a sinus headache in the morning. Try elevating the head on a few pillows to help the sinuses drain more easily.
How do you break up congestion naturally?
Salt water gargle- Gargling with warm salt water helps remove mucus from the respiratory tract. Inhaling steam- Pour hot water into a bowl, then bend over the bowl with a towel over vyour head. Inhaling the steam and vapors from the bowl will help in loosening phlegm.
Alternatives to oral decongestants are available. In the drug realm, antihistamines such as diphenhydramine (Benadryl), chlorpheniramine (Chlor-Trimeton), cetirizine (Zyrtec), and loratadine (Claritin) can help with a stuffy nose are safe for the heart. Nasal sprays deliver a decongestant right where you need it.
Sudafed (pseudoephedrine) and Sudafed PE (phenylephrine) are decongestant medications that treat nasal and sinus congestion. Sudafed is generally more effective at relieving nasal and sinus congestion than Sudafed PE, but it has more risks.
Pseudoephedrine (Sudafed) Other brand names: Galpseud, Boots Decongestant, Care Decongestant.
Studies have shown that pseudoephedrine is a much more effective decongestant than phenylephrine. Phenylephrine's decongestant effects may not be significantly different from that of a placebo. The effects of both drugs may be augmented with concurrent use of other products that affect rhinitis, such as antihistamines.
The most important difference between phenylephrine (PE) and pseudoephedrine (PDE) is that the efficacy as PE as a decongestant is unproven, whereas there is some evidence that oral PDE is effective.
Alternatives to oral decongestants are available. In the drug realm, antihistamines such as diphenhydramine (Benadryl), chlorpheniramine (Chlor-Trimeton), cetirizine (Zyrtec), and loratadine (Claritin) can help with a stuffy nose are safe for the heart.
OTC medications that may help include: Decongestants. These work by narrowing blood vessels to help reduce inflammation and swelling that cause sinus congestion. Such OTC medications (Sudafed, others) are available in liquids, tablets and nasal sprays.
Pseudoephedrine belongs to a group of medicines that act as decongestants by constricting small blood vessels in the nasal passages. Thus, less inflammation and congestion as the sinus tissue settles down a bit. It may improve thinking by improving breathing and sleep.
A number of decongestants are available for oral use, but the most commonly used decongestant is pseudoephedrine.
Is Sudafed or Claritin better for congestion?
They are both used to treat allergy and hayfever symptoms such as runny nose. However, Claritin is also used to treat allergic skin reactions such as such as hives and itching in people with chronic skin reactions, whereas Sudafed is used to treat nasal and sinus congestion.
Non-stimulant treatment options include steroid nasal sprays like fluticasone (Flonase) or triamcinolone (Nasacort 24HR).
Don't take pseudoephedrine (Sudafed) close to bedtime because it can cause difficulty falling asleep. Stop using pseudoephedrine (Sudafed) and contact your provider if you experience nervousness, dizziness, or trouble sleeping.