Can a dog overdose on amoxicillin?
Vomiting is the most likely effect with an overdose, but large overdoses of amoxicillin/clavulanate can be serious and can cause damage to the nervous system and liver. If you witness or suspect an overdose, immediately contact your veterinarian or an animal poison control center for further advice.
EFFECTS OF TOXICITY
Extremely high doses of amoxicillin may cause inflammation and damage to the kidneys or even formation of crystals in urine and subsequent kidney failure.
Ingestion of excess antibiotics often leads to gastrointestinal effects like vomiting, diarrhea, drooling, and loss of appetite. Some overdoses can lead to central nervous system effects like seizures or tremors. Contact a professional for advice if your dog gets an overdose of antibiotics.
Amoxicillin is dosed based on your dog's body weight and what infection your vet is trying to treat. A typical dosage used by many vets is 5 to 10mg per pound. This means a 50-pound dog would need to take 500mg twice a day. This is usually given for 10 to 14 days.
Dogs: The recommended dosage is 5 mg/lb of body weight twice a day. Cats: The recommended dosage is 50 mg (5–10 mg/lb) once a day. Dosage should be continued for 5–7 days or 48 hours after all symptoms have subsided.
Clinical signs of poisoning in a dog may include: Gastrointestinal signs: vomiting, diarrhea, extreme salivation, loss of appetite, and nausea or dry heaving. Internal bleeding: indicated by pale gums, a racing heart, coughing up or vomiting blood, weakness or lethargy, or a dog's falling over or collapsing.
The recommended dosage of Amoxicillin for dogs is 5 mg per lb of body weight, twice per day. The use should last for around 5 to 7 days or 48 hours after all symptoms resolve. It is essential to stick to these design guidelines as Amoxicillin overdoses in dogs are possible.
"Amoxicillin and other meds are generally the same antibiotics that humans use," said Dr. Jana Layton with Riverbrook Animal Hospital. It may seem like a way to pinch pennies.
In many pets, antibiotics can cause lethargy, nausea and/or a loss of appetite, which may make your pet less interested in eating their food. But it is crucial that your pet continues to eat, because their body needs the energy to continue fighting infection and repairing damaged cells.
Top Antibiotics for Dogs
Amoxicillin/Clavulanate—This antibiotic combo is related to Penicillin and is used to treat a broad spectrum of bacterial infections, including skin infections, infections in the respiratory system, gastrointestinal infections, and genitourinary infections.
How long does it take for amoxicillin to work in dogs?
This medication will take effect quickly, in about 1 to 2 hours. While effects may not be noted outwardly, gradual improvements are usually noticeable after a few days.
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Dosage and Administration.
Bottle Size | Amount of Water Required for Reconstitution |
---|---|
15 mL | 12 mL |
30 mL | 23 mL |

The dose of Amoxicillin is based upon the dog's weight. The correct dose is 5 milligrams per pound of body weight twice daily. So if your dog weighs 10 pounds, the dose would be 10 pounds x 5 mg/lb = 50 mg twice daily. The dose may be increased to 10 mg/lb twice daily in severe infections.
That said, with antibiotics, you should start to see some relief from symptoms as early as 24 hours after starting treatment, and should see significant improvement within 72 hours.
- NSAIDs (e.g. Advil, Aleve and Motrin) ...
- Acetaminophen (e.g. Tylenol) ...
- Antidepressants (e.g. Effexor, Cymbalta, Prozac, Lexapro) ...
- ADD/ADHD medications (e.g. Concerta, Adderall, Ritalin) ...
- Benzodiazepines and sleep aids (e.g. Xanax, Klonopin, Ambien, Lunesta)
One of the most common treatment options for poisoning in dogs is inducing vomiting. Other treatment may include medication to reduce pain and symptoms, overnight monitoring, or IV's for flushing out the toxins in the system. The cost of treatment can vary from $250 to $5,000.
Common signs of poisoning: Incoordination (ataxia), tremors, seizures, paralysis, and eventually death. The more an animal eats, the more severe the clinical signs may be. Signs can develop within 2 hours, but may be delayed as long as 36 hours.
Can I get antibiotics for my dog without seeing a vet? Yes, there are antibiotics that you can get without a vet prescription. Can you get antibiotics at a pet store? Many pet stores, including online pet stores, carry antibiotics that are safe to use for dogs.
Penicillin is generally considered safe for use in dogs, cats, horses, livestock, and many exotic pets.
Fortunately, most antibiotics are generally safe and rarely have serious effects on dogs.
Can taking antibiotics make a dog sick?
Antibiotics can certainly cause stomach upset in some animals. The most common side effects are vomiting and/or diarrhea. If she is not eating, be sure to contact your veterinarian, as sometimes infections can worsen even while under treatment with antibiotics.
This medication will take effect quickly, in about 1 to 2 hours. While effects may not be noted outwardly, gradual improvements are usually noticeable after a few days.
Overdose. Oral overdose of doxycycline in most instances will cause pronounced GI distress. If you suspect your pet or another animal was overdosed accidentally or has eaten this medication inadvertently, contact your veterinarian or the A.S.P.C.A.'s Animal Poison Control Center at 888.426. 4435.